Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 6;13:1967–1978. doi: 10.2147/OTT.S217087

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Ba et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

HIPK3 directly targeted miR-599 in ESCC. (A) Bioinformatics analysis revealed predicted binding sites between HIPK3 and miR-599. (B) Relative luciferase activity in TE-13 cells co-transfected with wild-type (HIPK3-WT) or mutant reporter plasmid (HIPK3-mut) and miR-599 mimic or negative control. (C) Cellular lysates from ESCC cells were used for RIP with an Ago2 antibody. The Ago2 protein level was detected by Western blot, (D) and the relative expression of HIPK3 and miR-599 in the immunoprecipitate was measured by RT-PCR. (E) The miR-599 expression in ESCC tissues and matched normal tissues. (F) Expression of miR-599 in the presence of si-HIPK3 or LV-HIPK3. (G) The relationship between HIPK3 and miR-599 in the ESCC organization.(** P <0.01).