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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Neurobiol Aging. 2019 Nov 29;87:89–97. doi: 10.1016/j.neurobiolaging.2019.11.016

Figure 3.

Figure 3.

Part A shows comparison of mean LC FA in young (i) and older adult (ii) cohorts as well as mean R2* in young (iii) and older adult (iv) cohorts. In A (i-iv) arrows show the approximate location of LC. Group comparisons are shown for AD (B), MD (C), and RD (D), and R2* (E). A statistically significant increase in mean LC FA was observed in the older cohort while reductions in mean LC RD and mean LC MD were seen in the older cohort. LC – locus coeruleus; MD – mean diffusivity; AD – axial diffusivity; RD – radial diffusivity; FA – fractional anisotropy.