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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Dec 3;5(3):354–363. doi: 10.1016/j.bpsc.2019.11.011

Figure 5. AMPA Connectivity and Depression.

Figure 5.

We compared NMDA and AMPA extrinsic connectivity estimates following ketamine (KET) administration with changes in both suicidal ideation (SI) and depression (MADRS – without SI) scores. Only MADRS (without SI) scores showed an association with connectivity – lower AMPA connectivity for the backward connection from insula to anterior cingulate was associated with lower depression symptomatology.