Table 1.
P. gingivalis | T. denticola | T. forsythia | F. nucleatum | Total bacteria | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Control | Infection | Control | Infection | Control | Infection | Control | Infection | Control | Infection | |
Baseline 1 | 16,981.09 ± 28,369.48 | 723.03 ± 407.71 | 1.18 ± 2.05 | 0.07 ± 0.07 | 8.43 ± 14.57 | 31.56 ± 23.59 | 59.47 ± 11.56 | 72.66 ± 28.24 | 553,248.72 ± 639,763.52 | 121,168.24 ± 80,829.30 |
(4:4; 100%) | (6:6; 100%) | (1:4; 25%) | (2:6; 33%) | (2:4; 50%) | (5:6; 83%) | (4:4; 100%) | (6:6; 100%) | (−) | (−) | |
Baseline 2 | 58.39 ± 85.52 | 77.71 ± 61.10 | 0.00 ± 0.00 | 1.03 ± 1.46 | 103.48 ± 54.06 | 151.63 ± 42.29 | 104.50 ± 36.60 | 149.37 ± 48.89 | 37,282.08 ± 16,477.93 | 30,052.84 ± 7,525.85 |
(6:6; 100%) | (6:6; 100%) | (0:6; 0%) | (2:6; 33%) | (6:6; 100%) | (6:6; 100%) | (6:6; 100%) | (6:6; 100%) | (−) | (−) | |
1 week | 299.89 ± 100.69 | 4,077.78 ± 1,805.15 | 1.19 ± 1.87 | 7.26 ± 4.58 | 1,096.65 ± 832.67 | 8,935.11 ± 3,838.25 | 550.51 ± 232.78 | 4,547.68 ± 2,009.55 | 183,983.00 ± 115,301.42 | 92,192.86 ± 50,283.58 |
(5:5; 100%) | (5:5; 100%) | (2:5; 40%) | (4:5; 80%) | (5:5; 100%) | (5:5; 100%) | (5:5; 100%) | (5:5; 100%) | (−) | (−) | |
4 weeks | 191.06 ± 68.67 | 15,943.21 ± 13,755.35 | 0.00 ± 0.00 | 0.00 ± 0.00 | 88.87 ± 75.33 | 21,464.59 ± 18,251.40 | 120.49 ± 29.79 | 12,066.57 ± 10,766.24 | 21,150.11 ± 5,938.39 | 746,180.73 ± 576,242.33 |
(6:6; 100%) | (6:6; 100%) | (0:6; 0%) | (0:6; 0%) | (6:6; 100%) | (6:6; 100%) | (6:6; 100%) | (6:6; 100%) | (−) | (−) | |
8 weeks | 73.40 ± 66.95 | 728.94 ± 1,059.93 | 0.00 ± 0.00 | 10.62 ± 15.06 | 2,005.86 ± 2,431.41 | 27,481.09 ± 5,043.55 | 296.09 ± 212.52 | 10,280.58 ± 2,788.89 | 32,852.47 ± 12,385.56 | 204,945.44 ± 67,419.62 |
(6:6; 100%) | (6:6; 100%) | (0:6; 0%) | (2:6; 33%) | (6:6; 100%) | (6:6; 100%) | (6:6; 100%) | (6:6; 100%) | (−) | (−) |
Actual numbers of bacteria/swab (mean ± s.d.)
(presence of periodontal pathogens in numbers of mice [%]).