Table 3.
Accuracy and recall (sensitivity) for cancer subtype identification (vertical search) among frozen section slides.
| Tumor type | WSI count | Patient count | Majority-5 | Majority-10 | Majority-20 | |||
|---|---|---|---|---|---|---|---|---|
| Accuracy | Recall | Accuracy | Recall | Accuracy | Recall | |||
| Brain | ||||||||
| GBM | 1102 | 582 | 94.19 | 94.19 | 92.74 | 94.37 | 92.92 | 93.65 |
| LGG | 695 | 501 | 82.58 | 82.59 | 80.28 | 83.02 | 81.00 | 83.31 |
| Endocrine | ||||||||
| ACC | 81 | 81 | 45.67 | 46.91 | 28.39 | 48.15 | 20.98 | 35.80 |
| PCPG | 174 | 170 | 85.63 | 86.78 | 86.20 | 89.66 | 83.90 | 86.78 |
| THCA | 514 | 478 | 97.08 | 97.67 | 97.47 | 98.44 | 97.85 | 98.83 |
| Gastrointestinal tract | ||||||||
| COAD | 830 | 449 | 63.73 | 69.40 | 56.62 | 74.10 | 60.00 | 78.43 |
| ESCA | 166 | 165 | 25.90 | 31.33 | 12.04 | 23.49 | 09.03 | 15.66 |
| STAD | 623 | 428 | 71.10 | 74.48 | 65.48 | 80.42 | 67.41 | 81.70 |
| READ | 328 | 170 | 14.32 | 19.21 | 05.48 | 14.63 | 02.13 | 8.54 |
| Gynecological | ||||||||
| OV | 1184 | 586 | 99.07 | 99.24 | 98.98 | 99.16 | 98.81 | 99.16 |
| CESC | 298 | 291 | 64.42 | 68.12 | 59.06 | 65.44 | 58.05 | 63.42 |
| UCS | 49 | 49 | 10.20 | 12.24 | 04.08 | 12.24 | 02.04 | 2.04 |
| UCEC | 685 | 524 | 90.07 | 90.80 | 89.05 | 90.80 | 89.34 | 91.68 |
| Hematopoietic | ||||||||
| DLBC | 57 | 45 | 91.22 | 91.23 | 80.70 | 87.72 | 73.68 | 78.95 |
| THYM | 124 | 124 | 97.58 | 97.58 | 95.16 | 97.58 | 95.16 | 95.97 |
| Liver, pancreaticobiliary | ||||||||
| LIHC | 392 | 370 | 93.36 | 93.88 | 92.60 | 94.64 | 93.62 | 94.90 |
| CHOL | 51 | 51 | 35.29 | 45.10 | 19.60 | 47.06 | 13.72 | 27.45 |
| PAAD | 216 | 181 | 91.66 | 91.67 | 90.74 | 93.52 | 90.74 | 93.98 |
| Melanocytic malignancies | ||||||||
| SKCM | 463 | 460 | 98.70 | 98.49 | 98.48 | 98.92 | 99.56 | 99.78 |
| UVM | 69 | 69 | 46.37 | 46.38 | 31.88 | 39.13 | 18.84 | 27.54 |
| Prostate/testis | ||||||||
| TGCT | 155 | 149 | 86.45 | 87.74 | 83.87 | 85.81 | 81.29 | 85.81 |
| PRAD | 600 | 485 | 98.33 | 98.33 | 98.33 | 98.33 | 98.50 | 98.67 |
| Pulmonary | ||||||||
| LUSC | 745 | 485 | 78.25 | 78.79 | 70.87 | 77.99 | 73.42 | 77.72 |
| LUAD | 806 | 500 | 68.23 | 69.11 | 64.14 | 71.34 | 66.12 | 70.84 |
| MESO | 83 | 83 | 27.71 | 32.53 | 14.45 | 26.51 | 03.61 | 21.69 |
| Urinary tract | ||||||||
| BLCA | 420 | 401 | 92.85 | 94.29 | 90.95 | 94.29 | 90.95 | 95.00 |
| KICH | 138 | 88 | 78.26 | 81.16 | 68.11 | 77.54 | 57.24 | 73.19 |
| KIRC | 1055 | 529 | 97.81 | 97.91 | 97.25 | 98.20 | 97.63 | 98.20 |
| KIRP | 367 | 282 | 62.12 | 67.30 | 51.22 | 63.76 | 47.13 | 58.86 |
Only those primary sites were considered for vertical search which had at least two subtypes in the repository. A positive correlation of 0.57 was measured between the number of patients and the highest accuracy.