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. 2020 Mar 10;10:4409. doi: 10.1038/s41598-020-61236-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Kaplan-Meier Recurrence Free Survival analysis and gene target expression heatmaps of survival subgroups generated with the union of the restrictive list gene targets of the 5-miRNA profile for RFS. (A) Unsupervised clustering, median RFS 17 (Group1) vs 105 months (Group2), log rank p = 0.007. (B) Supervised signed average prediction, median RFS 17 (Group1) vs 105 (Group2) months, log rank p = 0.001.