Table 2.
miRNA target gene set analysis for RFS and OS with experimentally verified miRNA gene targets sets for the 22-miRNA profile (miRNAs from the 5-miRNA profile are shown in bold).
| miRNA Gene Target Sets | Experimentally Verified Gene Target Lists | |||||
|---|---|---|---|---|---|---|
| Expansive | p-value (RFS) | p-value (OS) | Restrictive | p-value (RFS) | p-value (OS) | |
| hsa-miR-329-3p | 344 | 0.00232 | 0.00552 | 8 | 0.00098 | 0.01705 |
| hsa-miR-410-3p | 157 | 0.00462 | 0.05839 | 10 | 0.09067 | 0.05576 |
| hsa-miR-139-5p | 69 | 0.00541 | 0.03526 | 25 | 0.01062 | 0.29243 |
| hsa-miR-335-3p | 193 | 0.02183 | 0.33236 | 3 | 0.34046 | 0.732 |
| hsa-miR-487b-3p | 15 | 0.07972 | 0.02288 | 8 | 0.07061 | 0.0044 |
| hsa-miR-432-5p | 63 | 0.08432 | 0.03707 | 4 | 0.54804 | 0.35184 |
| hsa-miR-493-5p | 70 | 0.09954 | 0.09239 | 3 | 0.34046 | 0.47078 |
All miRNA gene target sets with significant or trending LS permutation test p-values for the expansive analysis are shown.