Table 4. Logistic regression analysis for the association of circulating microRNAsa with CKD (eGFR <60 mL/min/1.73 m2).
miR-17 (n = 484) | miR-21 (n = 484) | miR-150 (n = 493) | |||||
OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | ||
miRNA | Low | 1.00 | — | 1.00 | — | 1.00 | — |
Middle | 0.42 (0.23, 0.73) | 0.003 | 0.71 (0.41, 1.20) | 0.20 | 0.71 (0.41, 1.22) | 0.21 | |
High | 0.42 (0.24, 0.75) | 0.004 | 0.47 (0.26, 0.85) | 0.01 | 0.49 (0.27, 0.88) | 0.02 |
CI, confidence interval; eGFR, estimated glomerular filtration rate; OR, odds ratio.
Logistic regression analyses were performed after adjusting for sex, age, proteinuria, body mass index, systolic blood pressure, triglyceride, blood glucose, smoking status, alcohol consumption, exercise habit, and medication for non-communicable diseases.
aExpression level of microRNAs was used after logarithmic transformation.