Table 3.
Intra- and post-operative variables: comparison between the DHCA and MHCA + SACP groups.
| DHCA (n = 53) | MHCA + SACP (n = 61) | p value | |
|---|---|---|---|
| Intraoperative | |||
| CPB time (min) | 189.6 ± 41.2 | 146.9 ± 40.6 | 0.033 |
| ACC time (min) | 88.9 ± 19.6 | 75.9 ± 22.7 | 0.245 |
| DHCA/SACP time (min) | 32.2 ± 5.6 | 34.5 ± 4.2 | 0.321 |
| Lowest nasopharyngeal temperature (°C) | 18.9 ± 1.6 | 26.0 ± 2.1 | <0.001 |
| Lowest rectal temperature (°C) | 18.8 ± 1.7 | 25.7 ± 2.6 | <0.001 |
| Urine output during bypass (ml/kg/h) | 7.8 (2.3–30.0) | 7.2 (2.9–80.0) | 0.817 |
| Postoperative | |||
| 24-hour urine output (ml/kg) | 80.6 (48.7–596.0) | 100.6 (51.2–454.0) | 0.056 |
| 24-hour chest drainage (ml/kg) | 47.4 (15.2–145.0) | 28.9 (12.6–150.0) | 0.014 |
| Inotropic score (points)a | 17.2 ± 4.8 | 16.7 ± 4.3 | 0.871 |
| Consciousness recovery time | 3.8 ± 1.5 | 3.4 ± 1.2 | 0.342 |
| Mechanical ventilation time (h) | 94.0 (42.0–144.0) | 35.0 (15.4–80.3) | 0.008 |
| ICU stay (days) | 7.7 (5.0–15.0) | 3.9 (3.0–7.0) | 0.012 |
DHCA = deep hypothermic circulatory arrest; MHCA = moderate hypothermic circulatory arrest; SACP = selective antegrade cerebral perfusion; CPB = cardiopulmonary bypass; ACC = aortic cross-clamp; ICU = intensive care unit;
Notes: aInotropic score was calculated as: dopamine [μg/kg/min] + dobutamine [μg/kg/min] + epinephrine [μg/kg/min] × 100 + norepinephrine [μg/kg/min] × 100 + milrinone [μg/kg/min] × 10 + vasopressin (U/kg/min) × 10000.