Table 1.

Univariate and multivariate analysis of factors influencing DSS in 7156 PDAC patients with single-organ metastasis.

Variable		N	1-year survival rate	2-year survival rate	3-year survival rate	Median survival  ± SE (M)	Univariate analysis		Multivariate analysis
							95% CI	p value	HR	95% CI	p value
Single-organ metastasis		7156	16.95%	5.09%	1.95%	4.0  ± 0.08	3.84–4.16
Gender	female	3296	16.74%	5.28%	1.82%	4.0 ± 0.12	3.77–4.23	>0.05
	male	3860	17.11%	4.93%	2.00%	4.0 ± 0.11	3.78–4.22
Age	20–44 years	190	30.51%	8.49%	NA	8.0 ± 0.88	6.28–9.17	<0.0001 (20–64 years/65+ years)	1:1.24 (20–64 years/65+ years)	1.16–1.36	<0.0001
	45–64 years	3082	20.90%	6.82%	2.65%	5.0 ± 0.15	4.72–5.28
	65–74 years	2231	16.84%	4.36%	NA	4.0 ± 0.14	3.72–4.28
	75+ years	1653	8.09%	2.43%	NA	3.0 ± 0.10	2.80–3.20
Localization	head	2829	21.26%	5.24%	2.27%	5.0 ± 0.14	4.72–5.28	0.015 (head/body and tail)			>0.05
	body-tail	2496	19.44%	4.80%	1.73%	4.0 ± 0.14	3.72–4.28
	unknown	1831	NA	NA	NA	NA
Differentiation	G1, G2	790	22.27%	8.15%	1.82%	6.0 ± 0.31	5.39–6.61	<0.0001 (G1-2/G3-4)	1:1.31 (G1-2/G3-4)	1.17–1.50	<0.0001
	G3, G4	841	13.41%	3.54%	NA	4.0 ± 0.20	3.61–4.39
	unknown	5524	NA	NA	NA	NA
T classification	T4	1376	17.35%	4.59%	NA	5.0 ± 0.11	4.79–5.21	>0.05
	T1-T3	4139	18.73%	5.85%	2.10%	5.0 ± 0.20	4.60–5.40
	unknown	1641	NA	NA	NA	NA
Metastatic site	liver	6252	13.87%	2.99%	0.6%	4.0 ± 0.09	3.83–4.17	<0.0001 (others/lung)	1:0.87 (others/lung)	0.78–0.97	0.013
	lung	740	19.46%	4.60%	0.67%	6.0 ± 0.32	5.37–6.63
	bone	147	17.00%	NA	NA	6.0 ± 0.99	4.05–7.94
	brain	17	0	0	0	4.0 ± 0.08	2.67–5.33

NA: not available.