Figure 2.

Estimated values of the infectivity parameter β by model for both murine experimental systems. Each symbol represents the value estimated for one experiment. (a) Values estimated for murine P. berghei infection. Model a (base), c (comp. erythr.) and e (reticulocyte) show similar results whereas higher values were estimated for model b (bystander) and d (impaired maturation) (b) Estimated β –values for infection of humanized mice with P. falciparum using the mechanistic models f (const. RBC decay), g(dd. RBC decay), and h (human RBC). (c) Parasite growth rate p_gr and parasitemia at start of the exponential growth phase P₀ (72 h post-infection) estimated for model i (exponential). The laboratories are denoted by different symbols (not identified here).