Table 1.
Characterisation of liposome formulations
Size (nm) [b], [e] | Polydispersity | Zeta potential (mV) [a], [e] | %EE[c], [e] | Radiolabelling efficiency[d], [e] | |
---|---|---|---|---|---|
L-ALD | 156.6 ± 0.9 | 0.051 ± 0.02 | -12.5 ± 0.6 | 6.2 ± 0.2 | - |
DTPA-L-ALD | 152.4 ± 2.9 | 0.058 ± 0.013 | -11.1 ± 0.8 | 5.9 ± 0.6 | 82.6 ± 4.2 |
[a] Hydrodynamic diameter measured with dynamic light scattering. [b] Analysed with electrophoretic light scattering using 10 mM NaCl. [c] Measured with copper sulphate UV spectroscopy method. [d] Measured with quantitative autoradiography counting. [e] Data are represented as mean ± SD