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. 2020 Mar 3;11(2):e03341-19. doi: 10.1128/mBio.03341-19

TABLE 1.

Minor viral variants in OB- and WT-derived viruses

Passage	SNV call^a	No. (%) of mice with:
		PB2 L154I			PB2 K482R		PA E349K		PA-X/PA F35L^b		PA-X/PA F35L^c		NA G33GD		NS1 A202V		NS1 R211K
		No.^d	%^e		No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%
p0	23.5 ± 12.5
OBp1	43.0 ± 14.5								2	68	2	28
OBp2	112.3 ± 15.8								1	5					2	14	1	38
OBp3	111.3 ± 26.7	1		23					3	14	3	21			2	14	2	8
OBp4	133.7 ± 13.5	2		16	2	6			3	22	3	23	3	12	3	28	1	5
OBp5	90.8 ± 19.3	3		19	3	52	3	7	5	21	4	11	3	18	3	21	2	6
WTp1	36.4 ± 12.3				2	13					1	25
WTp5	78.3 ± 21.8				3	50			5	38	2	35			2	8
WTp10	85.3 ± 4.7								1	6					2	8

^a

Average ± SEM number of nonsynonymous and synonymous SNVs for each passage (n = 3 to 8 lung homogenates/passage).

^b

Nucleotide change of TTT→CTT.

^c

Nucleotide change of TTT→TTG.

^d

Total number of mice with ≥5% variants.

^e

Average relative frequency of mutation in samples with mutation.