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Larger mitochondrial swelling at constant calcium concentration. A similar extra‐mitochondrial calcium concentration (600 µmol/L) resulted in more swelling in isolated mitochondria from ZSF1‐obese animals compared to ZSF1‐lean animals. This effect was completely blocked by Ruthenium‐360 (Ru‐360), which blocked MCU activity. *P < 0.05 vs ZSF1‐lean, ⍺: compared to without Ru‐360
