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. 2020 Jan 21;38(3):410–421. doi: 10.1002/stem.3114

Figure 4.

Figure 4

The PYK2 and MEK/ERK signaling pathways are critical for Yoda1‐induced stimulation of hDP‐MSC migration. A‐C, Wound healing for cells from 9F (A), 20M (B), and 32F (C) under control condition (CTL) and cells exposed to 0.3 μM Yoda1 alone (Yoda1) or together with 10 nM PF431396 (PF + Yoda1). D, Summary of mean wound healing in three independent experiments for cells from 9F, 20M, and 32F under control condition (CTL) and cells exposed to Yoda1 alone or together with PF as shown in A‐C. E‐G, Wound healing for cells from 9F (E), 20M (F), and 32F (G) under CTL and cells exposed to 0.3 μM Yoda1 alone (Yoda1) or together with 1 μM U0126 (U0126 + Yoda1). H, Summary of mean wound healing in three independent experiments for cells from 9F, 20M, and 32F under control condition (CTL) and cells exposed to Yoda1 alone or together with U0126 as shown in E‐G. *P < .05 compared to control condition at the same time points, and # P < .05 and ## P < .001 compared to cells exposed to Yoda1