Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Confirmation of two clonal T‐cell populations by BaseScope ISH with TRB clone specific probes. (A) BaseScope probe design with the unique VDJ junctional sequence and TET2 mutation highlighted in red. (B) BaseScope in situ hybridization in case AITL030 with tonsil serving as a negative control. The TRB V7‐J1 probe identifies a diffuse cell population, whereas the TRB V27‐J2 probe reveals only scattered cells, confirming that they represent two independent clonal T‐cell populations.
