Egan 1976.

Methods	Quazi‐randomized Single unit Blinding of randomisation: no Blinding of intervention: no Complete follow‐up: yes Blinding of outcome measurement: yes
Participants	75 infants of Birthweight < 1,500 grams Receiving enteral feeds
Interventions	Kanamycin enteral (15 mg/kg/day in three doses) for 21 days
Outcomes	Incidence of NEC All deaths NEC‐related deaths Blood levels of kanamycin Microbiological colonisation rates
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	High risk	C ‐ Inadequate