Siu 1998.

Methods	Double blind randomized trial at one centre. Blinding of randomization: yes Blinding of intervention: yes Completeness of followup: not stated Blinding of outcome assessment: yes
Participants	140 preterm infants with birthweight <1500 grams, 48 hrs old. Excluded infants with lethal anomalies, major gastrointestinal anomalies and prior gastrointestinal surgery.
Interventions	Vancomycin oral 15mg per kg 8 hourly for 7 days or placebo (sterile water with one drop multivitamin per 20 ml).
Outcomes	Incidence of NEC, all deaths, microbial cultures.
Notes	Author provided information on NEC related deaths
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate