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OS according to the frequency of the reported cell populations
| Cut-off (median frequency) | Median survival (months) (95% CI) | p value |
|---|---|---|
| CD8+ lymphocytes | ||
| < 25.1% | 15.4 (5.8–25.0) | 0.18 |
| > 25.1% | 6.9 (0.1–13.7) | |
| CD8+ CD73 + lymphocytes | ||
| < 5.8% | 17.9 (4.9–30.9) | 0.06 |
| > 5.8% | 8.0 (0.8–15.2) | |
| CD8+PD-1+ lymphocytes | ||
| < 9.8% | 19.2 (10.1–28.3) | 0.008 |
| > 9.8% | 6.0 (0–12.8) | |
| CD8+PD-1+CD73+ lymphocytes | ||
| < 2.3% | 22.4 (13.6–31.2) | 0.001 |
| > 2.3% | 6.9 (0.8–13.0) | |
