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. Author manuscript; available in PMC: 2020 Mar 11.
Published in final edited form as: J Allergy Clin Immunol. 2008 Apr 18;122(1):195–201.e5. doi: 10.1016/j.jaci.2008.03.012

FIG 3.

FIG 3.

Airway inflammation and allergen-driven cytokine production are attenuated in yy-1+/− mice in a mouse model of asthma. WT and yy-1+/− (HET) mice were sensitized and challenged with OVA as indicated (see the Methods section), followed 48 hours later by analysis of lung lavage fluids by means of cytospin for eosinophils (A) and lymphocytes (B). Splenocytes were incubated with or without OVA (20 μg/mL) for 48 hours, and recall IL-4 expression was measured by means of ELISA (C) or RT-PCR compared with GATA-3 and GAPDH (D). Data are the means ± SEMs of 15 (Fig 3, A and B) or 20 (Fig 3, C) mice per genotype.