Table 2.
Plasma marker | β for Met/Cys-low vs. Met/Cys-high | p | β for Met/Cys-medium vs. Met/Cys-high | p |
---|---|---|---|---|
ApoA1 | 6.16 (− 3.33, 16.6) | 0.19 | − 4.05 (− 12.4, 5.04) | 0.35 |
ApoB | − 7.21 (− 22.4, 11) | 0.39 | − 3.08 (− 18.3, 15) | 0.70 |
ApoB/A1 | − 13.3 (− 28.4, 4.88) | 0.13 | − 0.9 (− 17.7, 19.3) | 0.92 |
Total cholesterol | − 1.7 (− 13.2, 11.4) | 0.78 | − 4.62 (− 14.8, 6.8) | 0.39 |
LDL | − 5.25 (− 21.2, 14) | 0.54 | − 6.69 (− 21.6, 11.1) | 0.41 |
HDL | 2.64 (− 5.26, 11.2) | 0.50 | − 0.68 (− 8.07, 7.3) | 0.85 |
Triglycerides | 8.51 (− 24, 55) | 0.63 | − 4.54 (− 31.7, 33.4) | 0.77 |
C-peptide | − 1.2 (− 19.5, 21.2) | 0.90 | − 4.19 (− 21.2, 16.5) | 0.65 |
Insulin | − 19.4 (− 45.6, 19.6) | 0.26 | − 10.8 (− 38.1, 28.6) | 0.52 |
Glucose | 0.48 (− 5.3, 6.61) | 0.87 | − 0.73 (− 6.26, 5.13) | 0.79 |
SCD16a | − 12 (− 27.8, 7.37) | 0.19 | − 15.7 (− 30.9, 2.84) | 0.087 |
SCD18a | 7.16 (− 4.46, 20.2) | 0.22 | 5.98 (− 5.02, 18.3) | 0.28 |
HOMA-IRb | − 21.3 (− 47.8, 18.7) | 0.23 | − 10.3 (− 38.7, 31.2) | 0.55 |
Body weight | − 0.29 (− 1.63, 1.08) | 0.66 | − 0.48 (1.70–0.75) | 0.42 |
Estimated marginal mean change in markers from baseline to the final study visit. Because all raw data values were log-transformed prior to analysis, the βs are given in units of per cent with corresponding confidence intervals
Met/Cys methionine and cysteine, apoA1 apolipoprotein A1, apoB apolipoprotein B, LDL low-density lipoprotein, HDL high-density lipoprotein, SCD stearoyl-CoA desaturase
aSCD16, C16:1n-7/C16:0; SCD18, C18:1n-9/C18:0
bHOMA-IR was calculated by (insulin/6) × (glucose × 18)/405