Effect of rupatadine (25 µM for 10 min) on IL-6 (a), IL-8 (b), IL-10 (c), IL-13 (d) and TNF release (e) release from hCBMCs measured by Milliplex microbead array (n = 3). Data were analyzed by the unpaired equal, 2-tailed, Student's t test. * p < 0.05, significance of comparisons between conditions and samples treated with the trigger alone, as shown by the corresponding brackets.