Table 1.
Baseline clinical and biochemical characteristics of ICU survivors and non-survivors patients on day 1 of admission.
| All n=56 | Survivors n=37 | Non-survivors n=19 | p | |
|---|---|---|---|---|
| Age, years | 61 | 61 | 65 | 0.94 |
| (48-70) | (49-69) | (48-71) | ||
| Male sex | 29 | 18 | 11 | 0.96 |
| ICU days | 8 | 8 | 8 | 0.94 |
| (4-14) | (4-14) | (4-16) | ||
| APACHE II score | 18 | 18 | 18 | 0.74 |
| (12-23) | (13-23) | (11-21) | ||
| Lactate, mmol/L | 2.85 | 2.4 | 3.3 | 0.16 |
| (1.9-5.1) | (1.9-3.5) | (2.35-6) | ||
| Bilirubin, mg/dL | 0.81 | 0,73 | 1.05 | 0.31 |
| (0.53-1.3) | (0.55-1.21) | (0.47-1.63) | ||
| Creatinine, mg/dL | 1.32 | 1.26 | 1.43 | 0.71 |
| (0.97-1.87) | (1.18-2.2) | (1.18-2.25) | ||
| CRP, mg/L | 172 | 153 | 201 | 0.94 |
| (99-245) | (100-243) | (93-286) | ||
| Hemoglobin, g/dL | 9.9 | 9.8 | 9.9 | 0.53 |
| (7.8-11) | (7.8-10.9) | (8.1-11.6) | ||
| White blood cells, | 15 | 13.3 | 17.3 | 0.15 |
| 109 /L | (11-21) | (10.1-17.9) | (12.7-22) | |
| Platelets , 109 /L | 182 | 186 | 130 | 0.03 |
| (104-216) | (150-217) | (93-206) | ||
| Causes of ICU admission, n; % | ||||
| Postoperative multiple organ failure | 38 | |||
| 67.9% | ||||
| Acute neurological condition | 7 | |||
| 12.5% | ||||
| Acute respiratory failure | 5 | |||
| 8.9% | ||||
| Acute circulatory failure | 4 | |||
| 7.1% | ||||
| Acute liver failure | 1 | |||
| 1.8% | ||||
| Multiple trauma | 1 | |||
| 1.8% | ||||
| MMP-9, ng/mL | 241.3 | 235.1 | 281.5 | 0.3 |
| (192.4-295.7) | (110.8-337.3) | (138.5-736.6) | ||
| TIMP-1, ng/mL | 335.7 | 287.7 | 816.6 | 0.01 |
| (262.2-455) | (202.3-458.2) | (227.2-1000) | ||
| MMP-9/TIMP-1, ratio | 0.62 | 0.63 | 0.57 | 0.3 |
| (0.49-0.78) | (0.44-0.87) | (0.32-0.84) |
data are presented as median and interquartile range (in bracket)
APACHE II , Acute Physiology and Chronic Health Evaluation; CRP , C-reactive protein; ICU, Intensive Care Unit; MMP-9, matrix metalloproteinase 9; TIMP-1, tissue inhibitor of matrix metalloproteinase 1