Table 4.

Kaplan-Meier estimates of overall survival and cancer-specific survival of colorectal cancer patients (n = 1,002).

Variable	Categories	Cases	Global survival			Cancer-specific survival
			Deaths	5 years	p-value	Deaths	5 years	p-value
All cases		1,002	489	58.2		422	62.3
Gender	Male	520	275	54.4	0.004	236	58.9	0.011
	Female	482	214	62.3		186	65.8
Age at diagnose	<50	290	134	62.0	0.066	133	62.4	0.368
(in years)	≥50 to <75	606	299	57.0		257	61.4
	≥75	106	56	55.0		32	67.7
Brazilian region of origin	South / Southeast	822	405	57.9	0.514	352	61.7	0.609
	Midwest	87	37	65.3		32	69.8
	North / Northeast	93	47	54.0		38	59.9
Primary tumor site	Right colon	250	111	60.0	0.289	90	65.7	0.168
	Left colon	466	221	58.9		195	62.2
	Rectum	285	156	55.6		136	59.6
Clinical stage (AJCC)	0/I	125	29	86.4	<0.001	15	93.9	<0.001
	II	376	126	72.5		97	78.2
	III	332	175	54.4		156	57.8
	IV	167	157	13.6		154	13.9
Histological type	Adenocarcinoma	937	458	58.5	0.004	395	62.6	0.009
	Mucinous	58	25	60.1		22	62.2
	Others	7	6	14.3		5	17.1
Histological grade	I/II	924	441	59.6	0.001	380	63.7	0.002
	III/Undifferentiated	63	41	37.4		35	41.1
Lymphovascular	No	621	227	69.7	<0.001	180	74.9	<0.001
invasion	Yes	300	200	40.6		184	42.8
Perineural invasion	No	731	301	64.9	<0.001	248	69.8	<0.001
	Yes	123	89	35.4		85	36.0
Presence synchronous	No	944	463	58.2	0.967	403	62.1	0.487
tumors	Yes	58	26	58.6		19	65.3
Presence of recurrence	No	698	245	67.8	<0.001	182	74.2	<0.001
	Yes	304	244	36.5		240	36.9
Treatment period	2000–2009	184	142	49.5	<0.001	138	50.2	<0.001
	2010–2014	818	347	60.3		284	65.3
Surgery	No	40	38	7.5	<0.001	37	7.7	<0.001
	Yes	961	450	60.4		385	64.6
Neoadjuvant chemotherapy	No	18	14	38.9	0.002	10	46.7	0.034
	Yes	159	80	59.1		71	62.7
Adjuvant chemotherapy	No	543	313	49.4	<0.001	260	54.6	<0.001
	Yes	442	169	69.1		157	71.0
Radiotherapy	No	793	376	58.6	<0.001	322	62.8	<0.001
	Yes, neoadjuvant	165	85	58.7		73	63.0
	Yes, adjuvant	21	7	81.0		7	81.0
	Yes, paliative	21	20	19.0		20	19.0
AFR	Low	347	171	58.0	0.403	148	62.2	0.308
	Intermediate	277	139	56.7		119	60.8
	High	310	137	60.2		114	64.9
EUR	Low	316	140	61.3	0.247	117	66.0	0.228
	Intermediate	315	160	55.0		136	59.1
	High	303	147	58.8		128	63.0
ASN	Low	445	215	57.6	0.833	184	62.1	0.819
	Intermediate	205	101	59.2		86	63.2
	High	284	131	58.8		111	63.3
AME	Low	404	190	58.9	0.859	167	63.0	0.949
	Intermediate	231	109	58.7		95	61.6
	High	299	148	57.2		119	63.2

Significant associations are indicated in bold.