Table 2.

Summary of findings for pregnancy subgroup: utility, RIO, or health state value information

Health state/outcome (categories of values and preferences)	Estimates of utilities	Certainty in evidence	Interpretation of findings
	No. of participants/studies
Pregnancy-related DVT (Bates et al24)	VAS: 46 (IQR, 30-65)	⊕⊕○○ Low certainty due to inconsistency and imprecision*,†	Women might possibly find pregnancy-related DVT having an important impact on their lives. There is likely an important variability for this assessment.
	123 participants from 1 study based on VAS
Pregnancy-related PE (Bates et al24)	VAS: 30 (IQR, 15-50)	⊕⊕○○ Low certainty due to inconsistency and imprecision*,†	Most women might possibly find pregnancy-related PE having an important impact on their lives. There is likely an important variability for this assessment.
	123 participants from 1 study based on VAS
Obstetric bleeding (Bates et al24)	VAS: 30 (IQR, 15-50)	⊕⊕○○ Low certainty due to inconsistency and imprecision*,†	Most women might possibly find obstetric bleeding having an important impact on their lives. There is likely an important variability.
	123 participants from 1 study based on VAS
Treatment with LMWH (Bates et al24)	Visual analog scale: 83 (IQR, 70-90)	⊕⊕⊕○ Moderate certainty due to imprecision†	Women may probably find treatment with LMWH having a small impact on their lives. There is some variability for this assessment.
	123 participants from 1 study based on VAS

Moderate certainty in evidence: We are moderately confident in the effect estimate; the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty in evidence: Our confidence in the effect estimate is limited; the true effect may be substantially different from the estimate of the effect.

IQR, interquartile range; VAS, visual analog scale.

^*Inconsistency due to important variability.

^†Imprecision due to small sample size.