| Methods |
RCT. Method of randomisation, allocation concealment and blinding of participants and investigators (including outcome assessors) not reported. Patients served as their own controls (i.e. one area of the same patient was treated with intervention while another similar area was taken as a control). |
| Participants |
50 patients (mean age 17.34) with a mean %TBSA: 14.7 |
| Interventions |
Antimicrobial release biosynthetic dressing (Hydron) versus SSD and exposed as routine |
| Outcomes |
Time to complete wound healing
Level of pain
Incidence of infection |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
High risk |
Each patient used as own control with matched burn ‐ sites not reported as randomised |
| Allocation concealment (selection bias) |
High risk |
No allocation concealment reported |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
Patients used as own control; no indication whether investigators/assessors blinded but unlikely |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
No details reported |
| Selective reporting (reporting bias) |
High risk |
Adverse events not reported |
| Other bias |
High risk |
Potential unit of analysis error as patients used as own control and sites may not be truly independent |
