| Methods |
RCT. No blinding employed. |
| Participants |
89 children with partial thickness scald burns covering 5% to 25%TBSA treated within 48 hours of injury and showing no initial signs of cellulitis or need for grafting |
| Interventions |
Biosynthetic dressing (Biobrane) versus twice‐daily application of SSD |
| Outcomes |
Time to complete wound healing
Hospital length of stay
Incidence of infection |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
"Computer generated randomisation table" |
| Allocation concealment (selection bias) |
Unclear risk |
No details reported |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
Care protocols not identical so participants, investigators and assessors not blinded. |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
10/89 (11%) of patients dropped out; reasons and group membership reported. Attempts to follow up dropouts by authors but these patients not included in the analyses. |
| Selective reporting (reporting bias) |
Low risk |
All prespecified outcomes reported |
| Other bias |
Unclear risk |
7/89 patients in study allocated treatment according to physician preference |
