Muangman 2010.
Methods | Single‐centre parallel RCT in Thailand. | |
Participants | 70 participants (male 32; female 38) with a mean age of 38 years presenting within 24 hours prior to study enrolment with superficial second degree burn < 15% TBS (mean %TBSA 2.8). Exclusion criteria included concomitant trauma; chemical/electrical burns; inhalation injuries; facial burns; underlying conditions that could interfere with treatment; restricted availability for out‐patient follow‐up; recent antibiotic use; pregnancy; wound dressing allergy | |
Interventions | Aquacel‐Ag hydrofibre dressing applied once versus daily application of 1% silver sulphadiazine. | |
Outcomes | Time to wound healing Pain Total dressing cost Total hospital cost Pain medication Transport cost |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: "Patients were randomised by computer..." Comment: probably done |
Allocation concealment (selection bias) | Unclear risk | Inadequate information reported to confirm concealment of allocation |
Blinding (performance bias and detection bias) All outcomes | High risk | Different care protocols so blinding of patients and investigators not feasible. Not clear whether assessor blinded: assumed to be at risk of detection bias. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | All participants followed‐up until wound had healed. Assumed that no losses to follow‐up occurred. |
Selective reporting (reporting bias) | Low risk | The outcomes described in the material and methods section were fully reported Expectation of wound infection would be low so reporting this outcome might not be relevant for this population |
Other bias | Low risk | None detected |