| Methods |
RCT. Method of randomisation, allocation concealment and blinding of participants and investigators (including outcome assessors) not reported. |
| Participants |
14 patients (mean age 23.4 years) with moderate to deep partial thickness burns (mean %TBSA: 13.3%). Burn wounds to hands, face, buttocks, feet and genitalia were excluded. |
| Interventions |
Biosynthetic dressing (TransCyte) versus twice daily application of SSD. |
| Outcomes |
Time to complete wound healing
Adverse events |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Participants acted as own control. Two burned sites on each patient "chosen randomly" but method of randomisation not described. |
| Allocation concealment (selection bias) |
Unclear risk |
Not reported |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
Care protocols were different so blinding of patients and investigators not feasible. Not stated whether there were separate assessors. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No reported withdrawals or dropouts |
| Selective reporting (reporting bias) |
Low risk |
All prespecified outcomes reported |
| Other bias |
Unclear risk |
Patients acted as own control so potential unit of analysis errors |
