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. 2020 Mar 4;8:132. doi: 10.3389/fbioe.2020.00132

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Copyright © 2020 Bloise, Massironi, Della Pina, Alongi, Siciliani, Manfredi, Biggiogera, Rossi, Ferruti, Ranucci and Visai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of Trastuzumab-conjugated gold nanoparticles with different sizes. (A) TEM images of 2.5 (a), 3.5 (b), and 5 (c) nm core diameter Au@PT nanoparticles (Scale bar = 200 nm), (B) XRPD, (C) UV-vis absorbance spectra (circle at 280 nm indicates the Trastuzumab peak), and (D) circular dichroism measurements of each Trastuzumab-conjugated gold nanoparticles families as function of core size.