Du 2003 (CPZ).
Methods | Allocation: randomised ‐ no further details. Blindness: not reported. Duration: 12 weeks. | |
Participants | Diagnosis: schizophrenia (CCMD‐2‐R). N=81. Sex: male and female. Age: 18 to 45 years. Excluded: organic psychotic patients; allergic to experiment drugs; with severe physical illness; pregnant or breast feeding women. | |
Interventions | 1. Clozapine: dose not reported. N=32. 2. Chlorpromazine: dose not reported. N=28. 3. Risperidone: dose not reported. N=21 | |
Outcomes | Leaving the study early. Unable to use ‐ Mental state: BPRS (group numbers not reported). Global state: GAS (group numbers not reported). Adverse events: TESS (group numbers not reported). |
|
Notes | CSG: 8466 | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | Randomised ‐ no further details |
Allocation concealment? | Unclear risk | No details |
Blinding? All outcomes | Unclear risk | Not reported |
Incomplete outcome data addressed? All outcomes | Low risk | Study attrition reported |
Free of selective reporting? | Unclear risk | No details |
Free of other bias? | Unclear risk | Unclear |