Table 2.
Some examples of inorganic nanoparticles for liver macrophage targeting.
| NPs type | Size/nm | Model | Effect | References |
|---|---|---|---|---|
| CeO2 | 53.36 ± 7.04 | Lipopolysaccharide induced severe sepsis in rats | Reduced expression of inflammatory macrophage mediators | (61) |
| Au | 7.4 ± 1.6 | Rat liver injury with ethanol and methamphetamine |
Downregulation of Kupffer cells activity | (62) |
| Glucomannan-silica | 27.6 ± 0.6 −28.89 ± 1.60 |
Murine inflammatory bowel disease | M2 polarization | (63) |
| SPIONs | ||||
| Dimercaptosuccinic acid | 65 | Murine and human M2 cells | Modification of M2 activation profile | (64) |
| 3-Aminopropyl-triethoxysilane | 54 | |||
| Aminodextran | 150 | |||