Table 2.
Sensitivity and specificity of the Centor and McIsaac scores at different thresholds
| Threshold | Sensitivity, % (95% CI) | Specificity, % (95% CI) | LR+ (95% CI) | LR− (95% CI) |
|---|---|---|---|---|
| Centor score | ||||
| 1 | 97.2 (96.4 to 97.8) | 10.1 (6.3 to 15.2) | 1.08 (1.05 to 1.14) | 0.28 (0.23 to 0.45) |
| 2 | 84.4 (81.4 to 87.0) | 36.7 (28.8 to 45.1) | 1.33 (1.19 to 1.50) | 0.43 (0.39 to 0.55) |
| 3 | 54.4 (48.7 to 60.0) | 72.4 (64.4 to 79.4) | 1.97 (1.46 to 2.40) | 0.63 (0.58 to 0.74) |
| 4 | 21.5 (16.6 to 27.2) | 93.7 (89.6 to 96.4) | 3.41 (1.83 to 4.97) | 0.84 (0.78 to 0.90) |
|
| ||||
| McIsaac score | ||||
| 0 | 99.7 (99.0 to 99.9) | 2.3 (0.3 to 10.7) | 1.02 (1.00 to 1.10) | 0.15 (0.09 to 0.35) |
| 1 | 97.5 (94.7 to 99.0) | 10.8 (2.8 to 28.4) | 1.09 (1.02 to 1.30) | 0.23 (0.17 to 0.39) |
| 2 | 88.0 (82.0 to 93.8) | 31.5 (14.2 to 54.3) | 1.30 (1.09 to 1.76) | 0.35 (0.28 to 0.47) |
| 3 | 68.7 (57.4 to 78.5) | 60.8 (39.9 to 78.8) | 1.75 (1.28 to 2.79) | 0.51 (0.44 to 0.58) |
| 4 | 40.0 (28.5 to 52.5) | 84.8 (70.8 to 93.4) | 2.64 (1.68 to 4.95) | 0.71 (0.62 to 0.78) |
| 5 | 16.1 (8.9 to 26.2) | 96.3 (90.8 to 98.7) | 4.32 (2.38 to 10.0) | 0.87 (0.79 to 0.93) |
CI = confidence interval. LR+ = positive likelihood ratio. LR− = negative likelihood ratio.