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. 2020 Feb 28;16(2):e1008380. doi: 10.1371/journal.ppat.1008380

Table 1. Treatment of neurons with small molecule inhibitors.

Small Molecule Source,
Catalog Number
Final Concentration Duration of Pre-treatment
Ciliobrevin A Sigma-Aldrich, 250401 50 μM 1 h
Cycloheximide Sigma-Aldrich, C7698 50 μg/ml 1 h
Dynasore Abcam, ab120192 150 μM 1 h
E64 Sigma-Aldrich, E3132 200 μM 4 h
5-(N-Ethyl-N-isopropyl)amiloride or EIPA Sigma-Aldrich, A3085 25 μM 1 h
Genistein Sigma-Aldrich, G6649 200 μM 1 h
Jasplakinolide Sigma-Aldrich, J4580 0.5 μM 20 min
Nocodazole Sigma-Aldrich, M1404 30 μM 1 h
PitStop2 Abcam, ab120687 25 μM 30 min
Wortmannin Cayman Chemicals, 10010591 200 nM 1 h

List of small molecule inhibitors used in this study along with their sources, final concentrations of use, and durations of pre-treatment of cells.