Skip to main content
. 2020 Mar 11;6(11):eaaz4157. doi: 10.1126/sciadv.aaz4157

Fig. 3. TGFβ2 stimulates fibronectin matrix production that mediates survival during mitogen withdrawal.

Fig. 3

(A and B) Survival of HCC1954 under control, TGFβ receptor inhibition (LY-364947, 5 μM), and TGFβ1 (1 ng/ml) or TGFβ2 (2 ng/ml) stimulation over (A) 7 days or (B) 28 days. (C) Immunofluorescence for fibronectin (green) and DAPI (blue) at day 28. (D) Expression of secreted TGFβ1, TGFβ2, or TGFβ3 in serum-starved cultures at 2 and 28 days in culture. P < 0.05 is denoted with *, P ≤ 0.01 with ** and P ≤ 0.0001 with ****.