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. 2020 Mar 6;13:2007–2019. doi: 10.2147/OTT.S240434

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© 2020 Gu et al.

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Silencing of TUG1 suppresses ovarian cell chemoresistance. (A) qRT-PCR was conducted to detect the effect of the TUG1 siRNA transfection of A2780/R and SK-OV-3 cells using one-way ANOVA analysis. (B) The cell viability of A2780/R cells was detected by CCK8 assay after TUG1 knockdown during PTX treatment. (C) The cell viability of SK-OV-3 cells was detected by CCK8 assay after knockdown of TUG1 during PTX treatment. (D) The colony assay was also used to detect the viability of A2780/R cells with or without PTX. (E) The colony assay was also used to detect the viability of A2780/R cells with or without PTX using one-way ANOVA analysis (p<0.05). *p<0.05; **p<0.01 and ***p<0.001.

Abbreviations: TUG1, taurine up-regulated 1; lncRNA, long noncoding RNAs; qRT-PCR, qualitative real-time polymerase chain reaction; PTX, Paclitaxel; CCK8, cell counting kit 8; NC, negative control; Si, Small interfering RNA.