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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Drug Discov Today. 2019 Feb 13;24(4):983–991. doi: 10.1016/j.drudis.2019.02.002

FIGURE 1.

FIGURE 1

Schematics of the transition in natural killer (NK) cell phenotype and functionality. Healthy cells are predominantly CD56dim/CD16+. However, during HIV infection, CD56−/CD16+ cells become dysregulated whereas the population of cytokine-secreting cells, CD56+/CD16dim, is reduced. Effective antiretroviral therapy (ART) treatment can partially recover healthy NK phenotypes.