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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: J Child Psychol Psychiatry. 2019 Sep 12;61(4):480–491. doi: 10.1111/jcpp.13123

Figure 1. Nodal definition and circuit coverage.

Figure 1.

A. Nodal definition. Whole-brain nodes based on a resting-state functional connectivity derived (Shen et al., 2013) atlas, which parcellated the brain into 268 regions. After removing nodes in the brain stem and cerebellum, 217 nodes were retained for the current study. B. Anatomical coverage of the depression-related circuit. From the nodes depicted in Figure 1 A, we selected all nodes whose centers fall within the anatomical boundaries of prefrontal cortex (PFC) including bilateral dorsolateral and ventromedial PFC and anterior cingulate cortex, as well as bilateral amygdala (AMY), and striatum (STR) including bilateral caudate, putamen, and pallidum.