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. 2020 Feb 10;11(9):2408–2420. doi: 10.7150/jca.35372

Figure 1.

Figure 1

High CDCA5 expression is a poor prognostic indicator in BC. (A) Immunohistochemistry staining of CDCA5 in BC tissue and peritumor tissue. Magnification: 40× and 200×. (B) Relative CDCA5 expression in various types of cancer. The data were based on the TCGA database. (C) CDCA5 expression in BC tissues (N=404) and normal bladder tissues (N=28) from the GEPIA website. (D) Normalized CDCA5 mRNA expression in BC tissues and normal bladder tissues from the Oncomine database (N=320). **P<0.01 Ta or T1 vs. normal and **P<0.01 T2 or more vs. normal. (E) Normalized CDCA5 mRNA expression in 20 pairs of BC tissues; BC tissues vs. normal bladder tissues. (F) OS rates stratified by low CDCA5 expression (N=201) and high CDCA5 expression from the TCGA database. The median was used as the dividing line for high or low CDCA5 expression. BC patients with high expression of CDCA5 had a worse OS rate than those with low expression of CDCA5. CDCA5, cell division cycle associated 5.