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. 2020 Feb 14;11(9):2580–2592. doi: 10.7150/jca.38179

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TGF-β blockade promoted apoptosis and suppressed migration of tumor cells. SW480 cells were co-cultured with TANs at a ratio of 1:2, and 1D11 was used to inhibit the expression of TGF-β in the culture system (2 µg/ml, 8 hours). The apoptosis of cells were detected by flow cytometry, and the migration of tumor cells were assessed by wound migration assay. A. Effect of 1D11 on the apoptosis of SW480 cells in each group. B. Effect of 1D11 on the apoptosis of TANs in each group. C. Effect of 1D11 on the migration of SW480 cells in each group.