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Characterization of the combination therapeutic–loaded liposomal system. (A) Cryogenic transmission electron micrograph of dual drug–loaded liposomes. Scale bar, 100 nm. (B) Schematic of dual loading of a small-molecule inhibitor (ETB, blue) into the hydrophobic, vesicular wall compartment and of a cytotoxic agent (DOX, green) into the aqueous, hydrophilic interior.
