Table 1.
Baseline characteristics of patients enrolled
| Characteristic | Dotinurad | Benzbromarone | |
|---|---|---|---|
| (n = 102) | (n = 98) | ||
| Sex | Male | 100 (98.0) | 98 (100.0) |
| Female | 2 (2.0) | 0 (0.0) | |
| Age (year) | Mean ± SD | 55.0 ± 10.3 | 54.7 ± 10.4 |
| Height (cm) | Mean ± SD | 170.9 ± 6.7 | 168.9 ± 7.1 |
| Weight (kg) | Mean ± SD | 75.7 ± 13.3 | 74.8 ± 12.6 |
| Serum uric acid (mg/dL) | Mean ± SD | 8.90 ± 1.16 | 8.92 ± 1.28 |
| eGFR (mL/min/1.73 m2) | Mean ± SD | 65.3 ± 11.5 | 66.2 ± 12.1 |
| Medical history of hyperuricemia | Number of patients (%) | 74 (72.5) | 75 (76.5) |
| History of gouty arthritis | Number of patients (%) | 83 (81.4) | 77 (78.6) |
| Existence of gouty tophus | Number of patients (%) | 1 (1.0) | 0 (0.0) |
| Drinking habits | Number of patients (%) | 67 (65.7) | 73 (74.5) |
| Classification of hyperuricemia | Uric acid underexcretion type (%) | 91 (89.2) | 90 (91.8) |
| Combined type or normal type (%) | 11 (10.8) | 8 (8.2) |
eGFR for male (mL/min/1.73 m2) = 194 × Serum creatinine−1.094 × Age−0.287
eGFR for female (mL/min/1.73 m2) = 194 × Serum creatinine−1.094 × Age−0.287 × 0.739 [17]
Definition of drinking habit: consumption of alcohol more than 3 days of the week and consumption of more than 500 mL beer or 60 mL of whisky in a day