Table 2.

Result of primary and secondary efficacy endpoints

Endpoint	Category	Dotinurad (n = 102)	Benzbromarone (n = 98)
Percent change in serum uric acid level from the baseline to the final visit	Mean ± SD (%)	45.9 ± 11.9	43.8 ± 11.8
	95% Confidence Interval	43.57 to 48.27	41.49 to 46.24
	95% Confidence Interval of difference between groups	− 1.27 to 5.37
	Two-sample t test	P = 0.224
Percentage of patients with serum uric acid level ≤ 6.0 mg/dL at the final visit	Number (%)	88 (86.2)	82 (83.6)
	95% Confidence Interval	78.04 to 92.29	74.84 to 90.37
	Fisher’s exact test	P = 0.693

Two-sample t test and Fisher’s exact test were adjusted with respect to dotinurad group versus benzbromarone group