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Treatment-related adverse events reported in two or more patients during Stage 1
| TRAE, n | Navoximod 400 mg (N = 3) | Navoximod 600 mg (N = 4) | Navoximod 1000 mg (N = 3) | Total (N = 10) |
|---|---|---|---|---|
| Any, n | ||||
| All grades | 1 | 2 | 3 | 6 |
| Grade ≥ 3 | 1 | 1 | 0 | 2 |
| Chromaturia, n | ||||
| All grades | 0 | 2 | 3 | 5 |
| Grade ≥ 3 | 0 | 0 | 0 | 0 |
| Maculopapular rash, n | ||||
| All grades | 1 | 0 | 1 | 2 |
| Grade ≥ 3 | 1 | 0 | 0 | 1 |
TRAE treatment-related adverse event
