TABLE 2.
Parameter | Univariate analysis | Multivariate analysis | ||||
HR | 95% CI | P-value | HR | 95% CI | P-value | |
Age (>50 vs. ≤50 years) | 0.632 | 0.304–1.312 | 0.219 | NA | ||
Menopause (Yes vs. No) | 0.670 | 0.329–1.362 | 0.258 | NA | ||
Histological grade (G3 vs. G1-2) | 1.434 | 0.740–2.782 | 0.286 | NA | ||
Tumor size (>2.0 cm vs. ≤2.0 cm) | 3.141 | 1.110–8.889 | 0.013* | 2.072 | 0.708–6.064 | 0.184 |
Lymph node status (Positive vs. Negative) | 2.807 | 1.350–5.836 | 0.006* | 1.514 | 0.645–3.553 | 0.340 |
TNM stage (III–IV vs. I–II) | 3.365 | 1.740–6.510 | 0.001* | 2.703 | 1.360–5.373 | 0.005* |
circGNB1 expression (High vs. Low) | 2.759 | 1.409–5.404 | 0.003* | 2.148 | 1.070–4.310 | 0.031* |
NA: not analyze; *P < 0.05, statistically significant.