TABLE 1.
Comparison of demographic and MRI characteristics between OHT subjects and NC.
| OHT (n = 18) | NC (n = 29) | Stats | |
| Age, years (mean ± SD) | 58.3 ± 9.8 | 57.9 ± 9.9 | p = 0.85 |
| Sex (M/F) | 10/8 | 15/14 | p = 0.9 |
| WM hyperintensities | p = 0.44 | ||
| Grade 0 | 61% | 72.4% | |
| Grade 1 | 39.9% | 24.1% | |
| Grade 2 | 0% | 3.5% | |
| Grade 3 | 0% | 0% | |
| Anatomical connectivity | No voxelwise differences | p > 0.005 uncorr | |
| GM matter volumes | No voxelwise differences | p > 0.005 uncorr | |
| Functional connectivity | |||
| Short range | OHT<NC in DMN, WMN, VAN, SN | p < 0.001 | |
| Long range | OHT<NC between DMN and SN OHT>NC between VIS I and II |
p = 0.0012 p = 0.0008 |
|
See text for details and abbreviations.