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. 2020 Mar 5;11:221. doi: 10.3389/fphar.2020.00221

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Copyright © 2020 Zhang, Song, Liang, Xie, Shi, Shi, Qiu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heat map of 21 metabolic biomarkers in each sample. The serum levels of the 21 metabolites significantly renovated by administration of JMT decoction at high dosage (JMT-H) in control (CON), STZ, STZ + JMT-H, and STZ + JMT-L groups (n = 6 per group). *Metabolites also significantly renovated by administration of JMT decoction at low dosage (JMT-L).