Table 3.
Estimation of linearity pharmacokinetics of maxacalcitol.
| Estimate (90% CI) of Slope | Taiwanese | Japanese | All |
|---|---|---|---|
| Parameter | N = 24a | N = 24b | N = 48c |
| C5 (pg/mL) | 1.06 (0.97–1.16) | 0.92 (0.73–1.12) | 1.00 (0.90–1.11) |
| AUClast (h・pg/mL) | 1.01 (0.86–1.16) | 1.04 (0.84–1.23) | 1.02 (0.88–1.16) |
| AUCinf (h・pg/mL) | 0.81 (0.69–0.94) | 0.89 (0.74–1.05) | 0.85 (0.73–0.98) |
N = 23 for AUCinf.
N = 22 for C5.
N = 46 for C5 and N = 47 for AUCinf.