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. 2020 Mar 5;14:145. doi: 10.3389/fnins.2020.00145

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Copyright © 2020 Brozzetti, Sacchetto, Cecchini, Avesani, Perra, Bongianni, Portioli, Scupoli, Ghetti, Monaco, Buffelli and Zanusso.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunocytochemical pattern of α-synuclein distribution in OM samples. Alpha-synuclein (4D6, red) shows a diffuse cytosolic distribution as well as a granular labeling around the margin of the plasma membrane of olfactory neurons and non-neuronal-shaped cells. Particularly, olfactory neurons show a thin granular labeling particularly localized at the dendritic knob [outlined square in (A), arrow in detail in (B)]. In the other cells, OMP-positive (green) α-synuclein shows a positivity around the plasmatic membrane. Scale bar (A): 20 μm. Scale bar (B): 10 μm.