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. 2020 Mar 5;14:145. doi: 10.3389/fnins.2020.00145

FIGURE 7.

FIGURE 7

Distribution pattern of 4R and 3R tau isoform expression. Double immunostaining with TUJ-1 (red) and mAb to 4R tau isoform (A,B, green) and 3R tau isoform (C,D, green). (A,B) The 4R tau isoform (green) is mainly localized in the cytosolic apical portion of TUJ-1-positive olfactory neurons, (red) in the proximity of the dendritic knob (arrows). As opposite, TUJ-1-positive cells are negative to the 3R tau isoform (green), which is unevenly distributed as granules in rounded cells, likely in differentiated stem cells, negative for the TUJ-1 antibody (C,D, *). All scale bars: 10 μm.